Serena Williams. Actress: Pixels. Serena Williams is one of the greatest female tennis players of all time. She earned her first Grand Slam singles title at the U.S. Open in 1999, and won a string of five Grand Slam singles title wins: the 2002 French Open, Wimbledon, and U.S. Open titles and the 2003 Australian Open and her second Wimbledon title in 2003, all by defeating her older sister, Venus...